| 貨號(hào) | 規(guī)格 | 價(jià)格 | 上海 | 北京 | 武漢 | 南京 | 購(gòu)買(mǎi)數(shù)量 |
|---|---|---|---|---|---|---|---|
| S80075-1mg | 98% | ￥60.00 | 6 | - | - | - |
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| S80075-2mg | 98% | ￥80.00 | 7 | - | - | - |
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| S80075-5mg | 98% | ￥140.00 | 7 | - | - | - |
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| S80075-10mg | 98% | ￥240.00 | 8 | - | - | - |
|
| S80075-25mg | 98% | ￥480.00 | 5 | - | - | - |
|
| S80075-50mg | 98% | ￥680.00 | 貨期：2-3天 | - | - | - |
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CP-466722 is a rapidly reversible inhibitor of ATM, with an IC50 of 4.1 μM, and has no effects on PI3K or closely related PI3K-like protein kinase (PIKK) family members.
| 產(chǎn)品描述： | CP-466722 is a rapidly reversible inhibitor of ATM, with an IC50 of 4.1 μM, and has no effects on PI3K or closely related PI3K-like protein kinase (PIKK) family members. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶點(diǎn)： | ATM:4.1 μM (IC50);ATM/ATR | ||||||||||||||||||||
| 參考文獻(xiàn)： | 1. Rainey MD, et al. Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation. Cancer Res. 2008 Sep 15;68(18):7466-74. 2. Guo K, et al. Development of a cell-based, high-throughput screening assay for ATM kinase inhibitors. J Biomol Screen. 2014 Apr;19(4):538-46. 3. W?sierska-G?dek J, et al. Interactions Between Ataxia Telangiectasia Mutated Kinase Inhibition, Poly(ADP-ribose) Polymerase-1 Inhibition and BRCA1 Status in Breast Cancer Cells. J Cancer Prev. 2014 Jun;19(2):125-36. | ||||||||||||||||||||
| 溶解性： | DMSO : 1 mg/mL (2.86 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存條件： | 2-8℃ | ||||||||||||||||||||
| 配置溶液濃度參考： |
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| 注意： | 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶(hù)參考交流研究之用。 |
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