| 產(chǎn)品描述： | Sal003 is a potent, specific and cell-permeable inhibitor of the eukaryotic translation initiation factor 2α (eIF2α) phosphatase. Sal003 is a derivative of salubrinal |
| 靶點： |
eIF2α phosphatase;Apoptosis |
| 體內(nèi)研究： |
Sal003 (20Μm; intrahippocampal injection; 8 minutes) impairs contextual memory in vivo |
| 參考文獻： |
1. Costa-Mattioli M, et al. eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell. 2007 Apr 6;129(1):195-206. 2. Yahiro K, et al. Regulation of subtilase cytotoxin-induced cell death by an RNA-dependent protein kinase-like endoplasmic reticulum kinase-dependent proteasome pathway in HeLa cells. Infect Immun. 2012 May;80(5):1803-14. |
| 溶解性： |
DMSO : ≥ 100 mg/mL (215.88 mM) |
| 保存條件： |
2-8℃ |
| 配置溶液濃度參考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.159 ml |
10.794 ml |
21.588 ml |
| 5 mM |
0.432 ml |
2.159 ml |
4.318 ml |
| 10 mM |
0.216 ml |
1.079 ml |
2.159 ml |
| 50 mM |
0.043 ml |
0.216 ml |
0.432 ml |
|
| 注意： |
部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。 |
上海工商
危險品化學品經(jīng)營許可證（不帶存儲）
營業(yè)執(zhí)照(三證合一)
北京