| 貨號(hào) | 規(guī)格 | 價(jià)格 | 上海 | 北京 | 武漢 | 南京 | 購(gòu)買(mǎi)數(shù)量 |
|---|---|---|---|---|---|---|---|
| S81200-2mg | 99% | ￥210.80 | 貨期：2-3天 | - | - | - |
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| S81200-5mg | 99% | ￥340.00 | 6 | - | - | - |
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| S81200-10mg | 99% | ￥530.40 | 4 | - | - | - |
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| S81200-25mg | 99% | ￥1088.00 | 貨期：2-3天 | - | - | - |
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| S81200-50mg | 99% | ￥2040.00 | 貨期：2-3天 | - | - | - |
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| S81200-100mg | 99% | ￥3100.00 | 貨期：2-3天 | - | - | - |
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PF-04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM
| 產(chǎn)品描述： | PF-04418948 is an orally active, potent and selective prostaglandin EP2 receptor antagonist with an IC50 of 16 nM | ||||||||||||||||||||
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| 靶點(diǎn)： | Prostaglandin Receptor;ProstaglandinReceptor | ||||||||||||||||||||
| 體內(nèi)研究： | PF-04418948 (oral gavage; 1, 3, and 10 mg/kg; once) attenuats the butaprost-induced cutaneous blood flow response | ||||||||||||||||||||
| 參考文獻(xiàn)： | 1. af Forselles KJ, et al. In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP2 receptor antagonist. Br J Pharmacol. 2011 Dec;164(7):1847-1856. 2. Birrell MA, et al. Selectivity profiling of the novel EP2 receptor antagonist, PF-04418948, in functional bioassay systems: atypical affinity at the guinea pig EP2 receptor. Br J Pharmacol. 2013 Jan;168(1):129-138. | ||||||||||||||||||||
| 溶解性： | DMSO : 130 mg/mL (317.53 mM; Need ultrasonic) | ||||||||||||||||||||
| 保存條件： | -20℃ | ||||||||||||||||||||
| 配置溶液濃度參考： |
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| 注意： | 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶(hù)參考交流研究之用。 |
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